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Department of Hematology & Transfusion Medicine Unit

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TMUAPS Speaker - Associate Professor Dr. Noor Haslina Mohd Noor

SPEAKER

DrNoorHaslinaTMUAPS

ASSOCIATE PROFESSOR DR. NOOR HASLINA MOHD NOOR
HEAD OF IMMUNOHAEMATOLOGY LABORATORY,
HOSPITAL UNIVERSITI SAINS MALAYSIA,
USM KUBANG KERIAN, KELANTAN, MALAYSIA  🇲🇾

Speaker CV

Associate Professor Dr. Noor Haslina Mohd Noor is the Head of Immunohaematology Laboratory, Hospital Universiti Sains Malaysia. She has Medical Degree from Universiti Sains Malaysia in 1996 and completed specialization in Master in Pathology (Haematology) in Universiti Sains Malaysia in 2005.

AP Dr. Noor Haslina research interest is TRANSFUSION IMMUNOHAEMATOLOGY, RED CELL ANTIGEN AND ANTIBODY and also GENERAL HAEMATOLOGY.

AP Dr. Noor Haslina holds research grants in immune thrombocytopenic purpura (ITP), haematology analyser evaluation, Lupus Anticoagulant evaluation, coagulation analyser evaluation and thalassemia trait diagnosis studies.

AP Dr. Noor Haslina publishes many articles, papers, publications in the field of coagulation, haematology, transfusion, cancer, bood donors and transfusion immunohaematology.

TMUAPS Speaker - PROFESSOR DR. ERICA WOOD

SPEAKER

ProfDrEricaWood

PROFESSOR DR. ERICA WOOD
IMMEDIATE PAST PRESIDENT, INTERNATIONAL
SOCIETY OF BLOOD TRANSFUSION (ISBT)),
MONASH UNIVERSITY, AUSTRALIA 🇦🇺

Speaker CV

Professor Erica Wood AO is a Haematologist at Monash Health, and Head of the Transfusion Research Unit in the School of Public Health & Preventive Medicine at Monash University, in Melbourne, Australia. She is an NHMRC Leadership Fellow, and leads an international research program in transfusion and blood disorders, including clinical trials and registries, and the NHMRC Blood Synergy program.

Erica is immediate past president of the International Society of Blood Transfusion, also past president of the International Haemovigilance Network and the Australian and NZ Society of Blood Transfusion. She is a member of several WHO expert groups on transfusion and anaemia, as well as a former RCPA Chief Examiner in Haematology. She contributes to the National Haemovigilance Advisory Committee and the TGA Advisory Committee on Biologicals.

TMUAPS Speaker - PROFESSOR DR. OYTIP NATHALANG

SPEAKER

ProfOytip

PROFESSOR DR. OYTIP NATHALANG
IMMUNOLOGY AND TRANSFUSION SCIENCE UNIT,
THAMMASAT UNIVERSITY, THAILAND 🇹🇭

Speaker CV

Major General Oytip Nathalang is a Professor, Director of Graduate Program, Graduate Program Faculty of Allied Health Sciences, Thammasat University 99 Moo 18 Paholyothin Road, Klongnung, Klongluang, Pathumthani 12120, Thammasat University, Rangsit Campus.

EDUCATION:

  1. B.Sc. (Medical technology) Mahidol University, Thailand 1975
  2. M.Sc. (Clinical Pathology) Mahidol University, Thailand                        1977
  3. Ph. D.  (Medical Science) Osaka City University, Japan                              2000 

TRAINING EXPERIENCE:

  1. Auckland Blood Transfusion Center, New Zealand                                                  1981-1982
  2. Tissue Typing Laboratory, Northwestern Medical School, Chicago, USA               1987-1988
  3. HLA Laboratory (Serology), Osaka Blood Center, Osaka, Japan                             1990
  4. HLA Laboratory, Australian Red Cross Blood Society, Melbourne and                   1992
  5. Perth, Australia
  6. HLA Laboratory (DNA testing), Osaka Blood Center, Osaka, Japan                       1994
  7. HLA Laboratory, Bristol, United Kingdom                                                               1996
  8. Ph.D. Dissertation JSPS-RONPAKU, Osaka City University, Japan                       1996-2000            

 

RESEARCH INTEREST:

Immunohematology and Immunogenetics

 

ADMINISTRATIVE EXPERIENCES:

  1. Member of the Association of Medical Technologist of Thailand                      1995-Present
  2. Member of the International Society of Blood Transfusion                                 2007-Present
  3. Executive Committee of the Thai Society of Hematology                                    2004- Present
  4. Executive Committee of the Thai Medical Technology Council                          2005-2010
  5. Councilor of Australasian and South East Asian Tissue Typing Association     2003-2008
  6. Councilor of Asia-Pacific Histocompatibilty and Immunogenetics Association 2008-2012
  7. Co-Editor of the Journal of Hematology and Transfusion Medicine                      2012-Present
  8. Editorial Board of Journal of the Medical Technologist                                         2012-Present
  9. Association of Thailand         
  10. Co-opted councilor of Asia-Pacific Histocompatibilty and                                    2015-2020
  11. Immunogenetics Association

 

AWARDS:

  1. Second Prize: Research article published in Royal Thai Army Medical Journal 1983
  2. Second Prize: Clinical research study, Royal Thai Army Medical Department 1997
  3. First prize: Research article published in Royal Thai Army Medical Journal 2004
  4. Ph. D. Thesis Awards, Osaka City University Medical School 2000
  5. Excellent Instructor Awards (Preclinical), Phramongkutklao 2005

    College of Medicine 

  1. Excellent in Academic Medical Technologist Alumni Awards, 2007

     Mahidol University

  1. First Prize: Research and Development Study, Royal Thai Army 2007
  2. Bronze Award: Thailand Research Expo Award, National Research 2012

    Council of Thailand           

  1. Excellent Researcher: Thammasat University Research Day 2012
  2. Excellent Research Presentation of Health Supra-cluster: National Research 2014

      University Project of Thailand, Office of the Higher Education Commission

  1. The highest citations in ISI, Scopus data award (2011-2015) 2016

      in Health Sciences of Thammasat University

  1. Excellent Medical Technologist of Thailand: The Association of Medical 2017

      Technologist of Thailand (AMTT)

  1. The highest international publications in ISI, Scopus data award 2017

      (2015-2016) in Health Sciences of Thammasat University

  1. The National Research Council of Thailand for the Good Research Award 2020
  2. The highest international publications in ISI, Scopus data award 2021

      (2018-2019) in Health Sciences of Thammasat University

  1. The National Research Council of Thailand for the Invention and 2022

       Innovation Award     

INTERNATIONAL PUBLICATIONS (2018-Present):

  • Nathalang O, Siriphanthong K, Petvises S, Jeumjanya N. Flow-cytometric analysis of HNA-2 expression and phenotypes among Thai blood donors. Ann Lab Med. 2018;38:362-66.
  • Chesor M, Mitundee S, Nathalang S, Thattanon P, Intharanut K, Tobunluepop P, Nathalang O. DI*A and DI*B allele frequencies among southern Thai blood donors. Indian J Hematol Blood Transfus. 2018;34:506-9.
  • Viboon S, Townamchai N, Phiancharoen S, Kupatawintu P, Dhitivat V, Nathalang O. Prevalence of antibody against angiotensin II type 1 receptor (AT1R) among Thai kidney transplant patients. Transplant Proc. 2018;50:1310-5.
  • Nathalang O, Ang RM, Kurin B, Limprasert S, Mitundee S, Leetrakool N, Intharanut K. Predicted S and s phenotypes from genotyping results among Thai populations to prevent transfusion-induced alloimmunization risks. Transfus Apher Sci. 2018;57:582-6.
  • Intharanut K, Sasikarn W, Mitundee S, Nathalang O. HNA-1, -3, -4, and -5 genotyping using multiplex PCR among southern Thais: Developing continual HNA-1 null detection. J Clin Lab Anal. 2019; 33: e22651.
  • Puobon U, Intharanut K, Mitundee S, Nathalang O. Determining of JK*A and JK*B Allele Frequency Distribution among Muslim Blood Donors from Southern Thailand. Malays J Med Sci. 2019; 26: 58-65.
  • Apipongrat D, Numbenjapon T, Prayoonwiwat W, Arnutti P, Nathalang O. Association between SLC44A2 rs2288904 polymorphism and risk of recurrent venous thromboembolism among Thai patients. Thromb Res. 2019;174:163-5.
  • Intharanut K, Khantisitthiporn O, Kupatawintu P, Leetrakool N, Mitundee S, Nathalang O. Establishment of KEL*01 and KEL*02 genotyping to recruit uncommon, Kell-positive, reagent red cells among Thai blood donors. Clin Lab. 2019; 65:1913-8.
  • Siriphanthong K, Petvises S, Thanongsaksrikul J, Intharanut K1, Nathalang O. A novel nonsense mutation found in the CD177 gene of Thai individuals with the HNA-2 null phenotype. Transfus Med. 2020; 30:30-6.
  • Nathalang O, Intharanut K, Leetrakool N, Mitundee S, Kupatawintu P. Impact of using genotyping to predict SERF negative phenotype in Thai blood donor populations. Blood Res. 2020; 55:107-111.
  • Intharanut K, Sasikarn W, Chusri W, Nathalang O. Two Thai Burmese descendants with A4GALT*01N.21, p phenotype, and anti-PP1Pk. Immunohematology. 2020;36:64-8.
  • Thattanon P, Thanongsaksrikul, Petvises S, Nathalang O. Monoclonal antibody specific to the Dia blood group antigen generated by phage display technology. Blood Transfus. 2020;18:366-73.
  • Thinley J, Sasikarn W, Chidtrakoon S, Nathalang O, Intharanut K. Blood group P1 prediction using multiplex PCR genotyping of A4GALT among Thai blood donors.Transfusion Med. 2021;31:48-54.
  • Wangmo T, Intharanut K, Leetrakool N, Mitundee S, Bejrachandra S, Nathalang O. Development of DO*A and DO*B allele detections to predict transfusion-induced alloimmunization risks in Thai populations. Clin Lab. 2021;67:2225-31.
  • Nathalang O, Intharanut K, Chidtrakoon S. High-resolution melting curve analysis to predict extended blood group phenotypes among Thai donors and patients. Transfus Med Hemother. 2022;49:163-71.
  • Tanwarawutthikul P, Intharanut K, Mitundee S, Nathalang O. RHCE*E and RHCE*e genotype incompatibility in a Southern Thai Muslim population. Asian J Transfus Sci. 2022;16:50-5.
  • Intharanut K, Ruanthong F, Chidtrakoon S, Nathalang O. Comparative analysis of a developed-probe-based real-time PCR and PCR-SSP for HLA-*B27 detection among Thai blood donors. Clin Lab. 2022;68:2363-70.
  • Apipongrat D, Roytrakul S, Prayongratana K, Charoenpitakchai M, Intharanut K, Laoruangroj C, Silpsamrit P, Nathalang O. Serum proteomic profiling reveals MTA2 and AGO2 as potential prognostic biomarkers associated with disease activity and adverse outcomes in multiple myeloma. PLoS One. 2022;17(12):e0278464.
  • Intharanut K, Nimnuch P, Naiwijarn W, Pimsiri W, Khantisitthiporn O, Nathalang O. Characteristics   of donors and modelling of the characteristics to possible forecast the repeat donors profiles at Thammmasat University Hospital. Indian  J Hematol Blood Tranfus. 2023;39:146-50.
  • Intharanut K, Khumsuk P, Nathalang O. Identification of Lutheran blood groups and genetic variants within KLF1 among Thai blood donors. Transfus Med Hemother. 2023, DOI: 10.1159/000528654
  • Nathalang O, Asisathaporn K, Intharanut K, Chaibangyang W, Leetrakool N, Mitundee S. Bejrachandra S. Genotyping approach to predict Coa and Cob antigens in Thai blood donor populations. J Blood Med. 2023;14:133-40.
  • Nathalang O, Intharanut K, Apipongrat D, Suttanon P. Association of HLA class II polymorphism and knee osteosrthritis in a Thai population. Clin Lab. 2023;69:975-83.
  • Intharanut K, Nathalang O, Suttanon P. Integrin subunit alpha M, ITGAM nonsynonymous SNP is associated with knee osteoarthritis among Thais: A case-control study. Curr Issues Mol 2023; 45: 4168-80.
  • Intharanut K, Khumsuk P, Nathalang O. Identification of Lutheran blood groups and genetic variants within KLF1 among Thai blood donors. Transfus Med Hemother. 2023, DOI: 10.1159/000528654
  • Bayat B, Lowack J, Audrain M, Croisille L, Curtis B, Dangerfield R, Esmaeili B, Grabowski C, Keller M, Kim H, Kroll H, Kvanka MM, Kwok J, Moritz E, Nathalang O, Nelson D, Nielsen KR, Pahn G, Poles A, Porcelijn L, Sachs UJ, Schönbacher M, Körmöczi GF, Kupatawintu P, Takahashi D, Uhrynowska M, Flesch B, Fung YL. World human neutrophil antigens investigation survey. Vox Sang. 2023 Aug 22. doi: 10.1111/vox.13500. Epub ahead of print. PMID: 37608544.

 

CASE REPORT

  • Intharanut K, Nathalang O. Identification of a novel KLF1 gene promoter variation (c.–251C > G) in a Thai blood donor with In(Lu) phenotype. Transfusion. 2023; 63:E32-E33.

REVIEW ARTICLE

  • Nathalang O. Red cell genotyping in Thailand: trends for blood transfusion in Asian populations. VOXS. 2020; 15: 310-4.

 

Proceeding

  • Nathalang O. Blood Group Genotyping. Proceeding the 8th TSH International Symposium (TSH-IS 2023) & 61st Annual Meeting of Thai Society of Hematology May 7-10, 2023: 77-84. tsh.or.th/meeting/tsh-is2023.

 

 

NATIONAL PUBLICATION

 1)   Chidtrakoon S, Jeumjanya N, Sasikarn W, Intharanut K, Nathalang O. Prevalence and   

       specificity of red cell alloantibodies in repeated antibody screening among Thai blood    

       donors. J Med Tech Assoc Thailand. 2018; 46: 6241-52.

  • Boonpokkrong P, Khanuntong S, Tupmongkol T, Srisuddee A, Phiancharoen S, Nathalang O. Evaluation of test kits for HLA allele detections using next generation sequencing technique. J Hematol Transfus Med. 2018; 28: 249-57.
  • Ounjai S, Ponraweethitikorn P, Kanunthong S, Srisuddee A, Phiencharoen S, Kupatawintu P, Attajarusit Y, Dhitavat V, Nathalang O. HLA-A, -B, and -DR frequencies in deceased kidney donors of the Organ Donation Centre, Thai Red Cross Society. J Hematol Transfus Med. 2019;29:175-81.
  • Rattakul A, Intharanut K, Nathalang O. The prevalence of red cell antibodies among patients and pregnant women in Pakchongnana Hospital. J Hematol Transfus Med. 2019;29:317-24.
  • Chinbordee K, Kukhuntod D, Tatawatorn A, Phiencharoen S, Attajarusit Y, Dhitavat V, Nathalang O. Pre-transplant factors influencing HLA crossmatch in deceaseddonor kidney transplantation. J Hematol Transfus Med. 2020;30:239-46.
  • Chidtrakoon S, Jeumjanya N, Intharanut K, Nathalang O. Analysis of pretransfusion testing events occurring in patients at Thammasat University Hospital. J Hematol Transfus Med. 2020;30:345-51.
  • Nimnuch P, Jeumjanya N, Intharanut K, Nathalang O. Trends in prevalence of transfusion-transmitted infections in blood donations at Thammasat University Hospital from 2017 to 2020. J Hematol Transfus Med. 2021;31:137-44.
  • Kukhunthod D, Thongpaknam S, Chinbordee K, Phiancharoen S, Kupatawintu P, Thanaketpaisarn Y, Luangtrakool K, Nathalang O, Dhitavat V, Chandanayingyong D. External proficiency testing in HLA typing for kidney transplantation in Thailand from 2009 to 2020. J Hematol Transfus Med. 2021;31:243-51.
  • Khosidworachet W, Mitundee S, Intharanut K, Bejrachandra S, Nathalang O. Frequencies of predicted Mia antigen among Southern Thai blood donors. J Southeast Asian Med Res. 2022; 6: e107.
  • Srisuddi A, Tupmongkol T, Thongpaknam S, Phiancharoen S, Kupatawintu P, Nathalang O, Attajarusit Y, Dhitavat V. HLA mismatch between deceased donors and kidney transplant recipients: a retrospective study from January 2019 to December 2021. J Hematol Transfus Med. 2022;32:243-51.
  • Thimthong N, Photi-a A, Traivaree C, Apipongrat D, Nathalang O. Using reticulocyte hemoglobin equivalent to determine iron deficiency anemia among Thai female adolescents. J Southeast Asian Med 2022; 6: e107.

TMUAPS Speaker - DR. CAROL LIM KAR KOONG

SPEAKER

DrCarolLim

DR. CAROL LIM KAR KOONG
O&G CONSULTANT, HOSPITAL AMPANG,
KUALA LUMPUR, MALAYSIA 🇲🇾

Speaker CV

Dr. Carol is a clinician in various Ministry of Health Hospitals (all regions – Northen, Sabah, East Coast & Klang Valley) Selangor Head of O&G Service; Head, Department of O&G, Ampang Hospital, Selangor. She is also a researcher -participated in various research projects in Ministry of Health, Malaysia. NPMC Clinical Supervisor for Master of O&G (MOG) & MRCOG candidates; Examiner for Master in Medicine (O&G). Clinical Practice Guidelines (CPG) – Cervical Cancer 2nd Edition (development group), Diabetes in Pregnancy (review committee), Haemophilia (review committee), Thalassaemia (review committee), SLE (review committee), Iron Deficiency Anemia (development group). National Postgraduate Medical Curriculum - O&G Team. Greater Klang Valley Speial Task Force for COVID-19 – member of Clinical Care Team. Klang Valley COVID-19 Unified Central Command – O&G Service Coordinator. College of O&G, Academy of Medicine Malaysia (COGAMM) Council Member, 2022-2024.

PUBLICATION – principal author for the following:
Queen Elizabeth Hospital Labour Room Protocol - MOH/P/SAB/04.04(HB). Patient Autonomy & Discharge Communication in MOH Hospitals -MOH/S/IPSK/11.08(RR). Patient Empowerment in Malaysia: The Doctor’s Perspective-MOH/S/IPSK/12.08(RR). Handoff Communication Process in MOH Hospitals -MOH/S/IPSK/10.08(RR). Effective Ways To Improve Handoff Communication: A Systematic Review -MOH/S/IPSK/27.09(RR). Sabah Obstetrics Shared Care Guidelines (SOSCG) – 1st Edition. SOP for “Use of Uterine Tamponade Balloon Catheter in Non-Specialist Hospitals in Sabah” – 2011. Getting patient blood management Pillar 1 right in the Asia-Pacific: a call for action -doi.org/10.11622/smedj.2019037 Malaysia Ministry of Health Post-COVID-19 Management Protocol, 2021.

PRESENTATION at Congresses – selected topics included:

  1. Fluid Collections in the Fetus ,24th Asian & Oceanic Congress of O&G (AOCOG2015), Kuching, Malaysia on 5 June 2015.
  2. Speaker for XIIth Malaysian National Hematology Scientific Meeting “Addressing Hemostatic Problems in Women”, Kota Kinabalu Malaysia, 24-25 April 2015 (on VTE, PPH)
  3. Rapid iron replenishment to save women and children’s lives, 23rd Regional Congress of the Perinatal Society of Malaysia, Kuala Lumpur, 21 April 2016
  4. Pulmonary Embolism, the silent killer of Mothers – how do we prevent this? National Heart Association Malaysia (NHAM) Annual Scientific Meeting 2017, Kuala Lumpur, 7-8 April 2017
  5. Various OGSM, Perinatal Society Malaysia congresses, Malaysia MOH teaching courses

RESEARCH EXPERIENCE

  1. Improving Patient Safety: Handoff Communication (Principal Investigator) – published Patient’s Unvoiced Needs (Co-investigator) – published.
  2. Predicting Preterm Labour: Evaluation Of Insulin-Like Growth Factor Binding Protein-1 As A Bedside Test (Supervisor) – principal investigator won Gold Medal for Oral Presentation at 2008 OGSM Congress.
  3. Health Outcome Research – Gestational Diabetes Mellitus in Sabah (Co-investigator) – Principal Investigator won 2nd place for Oral Presentation at 2013 OGSM Congress.
  4. Bakri postpartum balloon in the management of postpartum haemorrhage in Sabah Women's and Children's Hospital (SWACH): A Sabah Experience – this was a reference for KKM National Protocol on Uterine Tamponade in Management of PPH, 2012.
  5. A Case Series of VTE in Pregnant and Postpartum Patients in Temerloh Hospital (Co-investigator) – Principal Investigator won God Medal for Oral Presentation at 2016 OGSM Congress.

AREA OF INTEREST: Community Obstetric; Health System improvement

MEDICAL OUTREACH PROGRAM & VOLUNTARY ACTIVITIES

  1. Malaysia Medical Relief Society (Mercy Malaysia) 10th Medical Mission to Afghanistan, 3-20 March 2002 Medical and Humanitarian Mission to Somalia, 28 August 2011 – 8 September 2011
  2. Volunteer with the Good Shepherd missions in Nongkhai & Phuket, Thailand (2011/2012) and Taitung, Taiwan (2014). Jejak Desa outreach program to Sabah (2014 & 2016)
    Outreach program with the Society of the Helpers of Mary, Madarihat, India (2017)
    Enabler at QFFD Humanitarian Aid Clinic, Ampang, Selangor (2020)
  3. Volunteer doctor at Klinik Amar Muhajir, Serdang, Selangor (2021)