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Department of Hematology & Transfusion Medicine Unit

GRANTS

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  Project Title Principal Investigator Duration Amount Type of Grants
1 PERFORMANCE EVALUATION OF ABNORMAL WHITE CELL (WBC) DETECTION ON SYSMEX XN SERIES AND MINDRAY BC-6200 Dr Zefarina Zulkafli Nov 2024 - Oct 2025 RM47,780.40  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd  
2 PERFORMANCE EVALUATION OF XN-SERIES PLT-F AND BC-6200 PLT-O IN THE PRESENCE OF INTERFERING SUBSTANCES Dr Shafini Mohamed Yusoff Nov 2024 - Oct 2025 RM98,810.00  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd
3 RBC AND PLATELET PARAMETERS EVALUATION USING AUTOMATED HEMATOLOGY ANALYZER MINDRAY CAL-6000 Dr Zefarina Zulkafli Jan 2024 - Dec 2025
RM 15,200.00
 		 External Grant - UTAS Maju
4 WBC PARAMETERS EVALUATION USING AUTOMATED HEMATOLOGY ANALYZER MINDRAY CAL-6000 Dr Nurul Asyikin Nizam Akbar Jan 2024 - Dec 2025 RM20,000.00 External Grant - UTAS Maju
5 THE EVALUATION OF POINT-OF-CARE TESTING FOR DETERMINING HEMOGLOBIN LEVELS USING VERI-Q HB-MATE HEMOGLOBIN METER Associate Professor Dr Noor Haslina Mohd Noor Apr 2024 - Oct 2025 RM5,000.00  External Grant - Active Scientific
 6 ANALYSING THE RELATIONSHIP BETWEEN EXTENDED WHITE BLOOD CELL PARAMETERS AND INFLAMMATORY MARKERS IN INTENSIVE CARE UNIT PATIENTS WITH POSITIVE CULTURES Dr Razan Hayati Zulkeflee Nov 2023-Oct 2025 RM 15,464.00 External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd
 7 ASSESSMENT AND ESTABLISHMENT OF A REFERENCE INTERVAL FOR SYSMEX CN-3000 COAGULATION ANALYZER FOR HOSPITAL IN MALAYSIA Associate Professor Dr Noor Haslina Mohd Noor Dec 2022 - Dec 2024 RM10,045.00  External Grant - Sysmex Malaysia (National)
 8 PERFORMANCE EVALUATION FOR SYSMEX CN-3000 COAGULATION ANALYZER FOR HOSPITAL IN MALAYSIA  Dr Salfarina Iberahim Dec 2022 - Dec 2024  RM10,045.00 External Grant - Sysmex Malaysia (National)
 9 

Epigenetic Regulation in U266B1 and MM1.S Multiple Myeloma Cell Lines Treated with Sorafenib and Trichostatin A

 Associate Professor Dr Muhammad Farid Johan  Oct 2022 - Oct 2023 RM28,986.00 External Grant-Malaysian Society of Haematology
10 ROLE OF HAEMOCYTOMETRIC PARAMETERS IN PREDICTING SEVERITY OF COVID-19 INFECTIONS Dr Shafini Mohamed Yusoff July 2022 - Dec 2024 RM54305.00  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd
11 THE ROLE OF ADVANCED RED BLOOD CELL PARAMETERS FOR DETECTION OF ALPHA THALASSAEMIA TRAIT AMONG REGULAR WHOLE BLOOD DONORS Dr Zefarina Zulkafli Jun 2022 - May 2024  RM22,273.60  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd  
12 6-PARTS HAEMATOLOGY PARAMETERS EVALUATION USING ABBOTT ALINITY H Dr Zefarina Zulkafli Apr 2021 - Mar 2022
   
RM20,575.00
 		 External Grant - Geliga System
13 FAMILIAL CANCERS IN HOSPITAL USM : FUTURE DIRECTION OF INTERNAL DATABASE DEVELOPMENT FOR BIOBANKING Professor Dr Rosline Hassan Feb 2020 - Aug 2022
RM 17,000.00
 		 External Grant - NUMED
 14 EXPLORING POTENTIAL WHITE BLOOD CELL PARAMETERS FOR DIAGNOSIS AND MONITORING SEPSIS IN THE INTENSIVE CARE UNIT   Professor Dr Rosline Hassan Oct 2021 - Jun 2024 RM39,216.00  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd  
15 5-PARTS AND 3-PARTS HAEMATOLOGY PARAMETERS EVALUATION USING DYMIND DH73 ANALYSERS Associate Professor Dr Noor Haslina Mohd Noor Oct 2020 - Nov 2021 RM10,500.00  External Grant - ANTAH Sri Radin
 16  CLINICAL UTILITY OF MICRO-R AND HYPO-HE IN THE DIAGNOSIS OF THALASSEMIA TRAIT IN HOSPITAL UNIVERSITI SAINS MALAYSIA Associate Professor Dr Rosnah Bahar  Oct 2021 - Dec 2023 
 
RM53,363.56
 		  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd  
 17 CLINICAL UTILITY OF MICRO-R AND HYPO-HE IN THE DIAGNOSIS OF LATENT IRON DEFICIENCY IN HOSPITAL UNIVERSITI SAINS MALAYSIA Dr Zefarina Zulkafli Oct 2021 - Jun 2024 RM25,365.68  External Grant (INTERNATIONAL) - Sysmex Asia Pacific Pte Ltd  

 

 

  Project Title Principal Investigator Duration Amount Type of Grants  
 1 Proteomics Analysis of Multiple Myeloma Cell Lines Induced by Epigenetic Regulators and Histone Deacetylase Inhibitors  Assoc. Prof. Dr. Muhammad Farid Johan Jul 2021-Oct 2023 RM10,000.00 GIPS Grant  
 2 SARS-COV-2 GENOMICS SURVEILLANCE Prof. Dr. Rosline Hassan 1 Nov 2021 - 31 Dec 2024
RM624,000.00 
 MOSTI  
 3 3D PRINTED TUMOUR MODEL: INVESTIGATION OF BIOINK MICROENVIRONMENT EFFECTS AND THERAPEUTIC RESPONSES ON RHO/ROCK SIGNALLING PATHWAY Dr. Lee Si Yuen 1 Nov 2020 - 31 Oct 2024
RM203,500.00
 		 FRGS  
 4 Investigating and understanding the genetic (HLA, immunoregulatory genes, cytokine gene) and immunomodulatory factor of RBC alloimmunization in the pregnant woman  Dr. Mohd Nazri Bin Hassan  1 Nov 2020 - 31 Oct 2023 RM151,308.00   FRGS  
 5 A Study on Molecular Dysfunctions and Key Regulator Pathways in Acute Myeloid Leukaemia- Normal Karyotype by Integrated Analysis of transcriptomic, MicroRNA, and Metablomic  Prof. Dr. Rosline Hassan May 2020-Apr 2023
RM 15,000.00
 		 GIPPS  
 6 Investigating and understanding the genetic risk factors (cytokine, MHC, KIR, TLR, IgG receptor, platelet glycoprotein, MBL and immunoglobulin genes) of immune thrombocytopenic purpura (ITP): towards a novel strategy for diagnosis and management of ITP  Assoc. Prof. Dr. Noor Haslina Mohd Noor  1 Sept 2019 - 31 Aug 2022  RM159,268.00  FRGS  
 7 The immunoregulation of high dose Vitamin C and low dose chemotherapy (HiCLoChemo) as a novel cancer chemoimmunotherapeutic in breast cancer rats model  Prof. Dr. Rosline Hassan  1 Sept 2019 - 31 Aug 2022  RM181,700.00 FRGS   
8 
Elucidating the genetic basis of Xmn1-HBG2 and HBS1L-MYB single nucleotide polymorphisms (SNPs) in controlling the hemoglobin F (HbF) level in patient with acquired anemia.
 Dr. Zefarina Zulkafli  1 Sept 2019 -30 Nov 2023  RM106,530.00  FRGS  
 9 Elucidating the role of DNA methylation as modifiers of beta-globin gene in HbE/Beta Thalassaemia via an in-vitro model of epigenetic expression system  Assoc. Prof. Dr. Muhammad Farid Johan  1  Jan 2019 - 30 Sept 2022  RM180,800.00  FRGS  
10 Impact on the Environment Assets: Nutrition and elucidating the immunological factors as contributing to the health status of the local election in Kelantan Flood Victims  Prof Dr Rosline Hassan  Apr 2015 - Mac 2016  RM137,200.00  TRGS  
11  UNDERSTANDING THE INEFFECTIVE ERYTHROPOIESIS IN TRANSFUSION DEPENDENT THALASSAEMIA; ROLE OF AHSP AND TELOMERE LENGTH AS CONTRIBUTION FACTORS  Prof Dr Rosline Hassan Dis 2014 - Nov 2016  RM130,000.00 

FRGS

  
 12 Mechanism of Action Under current regulator JAK / STAT signaling pathway in Flt3-ITD-resistant cells Acute myeloid leukemia, the Ministry of Education Malaysia Dr Muhammad Farid Johan  August 2014 - December 2016   RM124,526.00  FRGS
 13 EFFECTS OF MALAYSIAN RED EDIBLE PLANTS AS ANTI CANCER THERAPY ON RTK/RAS SIGNALLING PATHWAY IN LEUKAEMIC CELL LINES  Dr Muhammad Farid Johan  Dec 2009 - Dec 2011  RM50,000.00  FRGS
 14 ISOLATION, CHARACTERIZATION AND DIFFERENTIATION, POTENTIAL OF MESENCHYMAL STEM CELL FROM WHOLE HUMAN PLACENTA  Prof Dr Rosline Hassan Oct 2007 - Oct 2009   FRGS
 15 A STUDY TO INVESTIGATE THE EFFECT OF HORMONE REPLACEMENT THERAPY AND COMMERCIALLY AVAILABLE VITAMIN E ON PLATELET ACTIVATION MARKERS AS DETERMINED BY FLOW CYTOMETERY IN POST-MENOPAUSAL WOMEN Prof Dr Rosline Hassan July 2007 - Jun 2009   Science Fund, MOSTI

 

 

 

 

Project Title

Principal Investigator

Duration 

Amount

Type of Grants
1  Genotypic Profiling of RHD, RHCE, and RHAG and Their Association with RhCE Phenotypes in RhD-Negative Women of Child-bearing Age at USM Hospital DR SITI ASMAA MAT JUSOH 01/09/2024 - 31/08/2026 RM45,979.00  USM Short Term
2 
EXPLORING THE PREVALENCE OF DI(A) ANTIBODIES AND DIEGO ANTIGEN AMONG PATIENTS IN HOSPITAL UNIVERSITI SAINS MALAYSIA
 
Dr Nur Ilyia Syazwani Saidin
 
 		 Sep 2024-Oct 2026  RM45,984.00  USM Short Term 
 3
GENE MUTATIONS IN MYELOPROLIFERATIVE NEOPLASM AND ITS ASSOCIATIONS WITH CLINICAL AND LABORATORY CHARACTERISTICS
  Dr Razan Hayati Zulkeflee  Dec 2023-Nov 2025 RM46,000  USM Short Term  
4 
EVALUATION OF COAGULATION FACTORS ACTIVITY AND STERILITY IN THAWED AND DOUBLE THAWED REFROZEN FRESH FROZEN PLASMA (FFP),
 Dr Marne Abdullah  Nov 2023-Oct 2025
RM 29,023.00
 		 USM Short Term 
 5 PROTEOMICS ANALYSIS OF MULTIPLE MYELOMA CELL LINES INDUCED BY EPIGENETIC REGULATORS AND HISTONE DEACETYLASE INHIBITORS ASSOC. PROF. DR. MUHAMMAD FARID JOHAN 1 JULY 2021 - 30 JUNE 2023 RM10,000.00 GERAN INSENTIF PEMBANGUNAN SISWAZAH- PhD (GIPS-PhD)
 6 Haemostatic, Inflammatory and haematological Biomarkers among Surgical Based patients (Orthopaedics and Surgery) with Prolonged Immobilization and risk of Venous Thromboembolism. Dr Salfarina Iberahim  1 Aug 2020 -    31 July 2022  RM34,020.00 USM Short Term
 7 The Role of Thalassemic Red Cell in the Mechanism Process of Hypercoagulable State in Thalassemia Intermedia and Major Patient PROFESOR MADYA DR. ROSNAH BINTI BAHAR 1 Nov 2020 - 31 Oct 2023 RM42,000.00 USM RUi
 8 Detection of minimal residual disease using flor cytometry in acute lymphoblastic leukaemia Dr. Shafini Mohamed Yusoff  Aug 2019 - July 2020 RM23,472.00 Bridging
 9  ELUCIDATING THE ROLE OF TUBB2A, CCNA1 AND SOCS3 DOWN-REGULATION IN ACUTE MYELOID LEUKEMIA (AML) CELL LINES TREATED WITH DNA METHYLTRANSFERASE AND HISTONE DEACETYLASE INHIBITORS Assoc. Prof. Dr. Muhammad Farid Johan  Jan 2018 - Jan 2019   RM10,000.00  Bridging
 9 The Development Of Erythroid Precursor Model From Cd34-Peripheral Blood Mononuclear Cells Prof Dr Rosline Hassan Jan 2018 - Jan 2019  RM 10,000.00  Bridging
 10 EVALUATION OF THE OXIDATIVE STRESS LEVEL IN HBE/ß- THALASSEMIA PATIENTS Prof Dr Rosline Hassan Dec 2018 - Dec 2019 RM 24,880.00  Bridging
 11  RED CELL ALLO AND AUTOIMMUNIZATION IN CANCER PATIENTS AT HOSPITAL UNIVERSITI SAINS MALAYSIA  Dr Mohd Nazri Bin Hassan  Aug 2018-May 2021  RM32,955.30 USM Short Term
 12  THE DEVELOPMENT OF NOVEL BACULOVIRUS INSECTICIDE EXPRESSING MULTIPLE INSECTICIDAL PROTEIN FROM THE NATURAL ENEMIES OF RED PALM WEEVIL (Rhynchophorus ferrugineus)  Assoc. Prof. Dr. Muhammad Farid Johan  NOV 2017 - JULY 2021  RM93,106.00  USM RUi
 13 PROTEIN EXPRESSION OF EPIGENETICALLY RE-EXPRESSED GENES INDUCED BY TRICHOSTATIN A AND 5-AZACYTIDINE TREATMENTS IN ACUTE MYELOID LEUKEMIC CELL LINES   Assoc. Prof. Dr. Muhammad Farid Johan  Aug 2017 - Oct 2017  RM2,950.00  Incentive
 14  Understanding the Apoptotic Effects of Epigenetic Modification Drugs on Proteome Profiles of Myeloid and Lymphoid Cell Lines   Assoc. Prof. Dr. Muhammad Farid Johan  Aug 2017 - Oct 2017 RM3,000.00   Incentive
 15  DNA Methylation of IGSF4 and LARP2 genes as Epigenetic Modifiers in HbE/β Thalassemia Phenotypic Heterogeneity   Assoc. Prof. Dr. Muhammad Farid Johan  Aug 2017 - Oct 2017 RM3,000.00   Incentive
 16

Identification of Genetic Aberration in Normal Cytogenetic AML and Correlation with Clinico Biological Parameters

 Dr Marini Ramli Mac 2016 - Feb 2020 RM178,000.00 USM RUi
 17 Elucidating the mechanism of ineffective erythropoiesis Contributes to Disease Severity In Beta Thalassemia Prof Dr Rosline Hassan July 2015 - June 2017 RM142,404.00 USM RUi
18  A  Pilot Study in laboratory and clinical features of Rare Anti-phospholipid antibodies in pre-eclampsia patients, USM Dr Wan Mahmood Wan Haslindawani Jun 2015 - Mei 2017 RM46,920.00 USM Short Term
 19 Impact on environmental assets : Elucidating the nutritional and immunological factors as the contributing to health status among flood victim in Kelantan Prof Dr Rosline Hassan Apr 2015-Apr 2016 RM137,200.00 TRANSDICIPLINARY RESEARCH GRANT SCHEME (TRGS)
 20  Monocytes and lymphocytes AS EX new hematological markers To detect Dengue fever  Dr Shafini Mohamed Yusoff  August 2014 - August 2016    USM Short Term
21   Factors contributing to the success of Autologous Peripheral Blood Stem Cell Transplantation In lymphoproliferative disease at Hospital Universiti Sains Malaysia Dr Mohd Nazri Hassan   September 2014 - August 2016  RM38,335.00  USM Short Term
22  EVALUATION OF CAPILLARY ELECTROPHORESIS IN DETECTING HAEMOGLOBIN E AMONG NEONATES DELIVERED IN HUSM  Assoc. Prof Dr Rosnah Bahar  Dec 2014 - December 2016  RM40,000.00   USM Short Term
23 Understanding the ineffective erythropoiesis in transfusion dependent thalassaemia; role of AHSP and telomere length as contribution factors Prof Dr Rosline Hassan Dec 2014-Nov 2017 RM130,000.00 FRGS
 24  Evaluation of immune markers and haemostatic Among the most frequent Whole Blood Donors  Assoc. Prof. Dr Rapiaah Mustaffa  November 2014 - November 2016 RM39,740.00   USM Short Term 
25   A Pilot Study on Clinical and Laboratory Profile Blood Donor WITH erythrocytosis  Assoc. Prof. Dr Mohd Noor Noor Haslina  September 2014 - August 2016 RM43,813.00   USM Short Term
 26

Development of In Vitro Whole Blood (WB) Clot Method To Study fibrinolytic activity and haemostatic Properties Of Pure caffeic acid phenethyl ester (CAPE) Compound Propolis And Local

Prof Dr Wan Zaidah Abdullah

2013 - 2016

 -

  USM RU

 
 27 HYPERCOAGULABLE STATE AMONG THALASSEMIA MAJOR AND INTERMEDIA PATIENTS Assoc. Prof Dr Rosnah Bahar Oct 2012 - Oct 2014 RM40,000.00   USM Short Term
28 Identification of Differentially Expressed Genes & Epigenetic Inactivation Profiling of Various Cytogenetic Rearragements in Primary AML cell lines

Dr Muhammad Farid Johan

 Nov 2011 - Nov 2014 RM240,662.25 USM RU  
29  In Vitro Study of Mechanism of Resistance to Tyrosine Kinase Inhibitors in Leukaemia: Effects on Methylation in JAK/STAT Signalling Pathway Dr Muhammad Farid Johan Mar 2010 - Feb 2012 RM40,000.00 USM Short Term  
30 FLOW CYTOMETRIC ANALYSIS OF NUCLEAR DNA PLOIDY AND PROLIFERATIVE ACTIVITY IN ACUTE LYMPHOBLASTIC LEUKAEMIA  Dr Shafini Mohamed Yusoff Feb 2009 - Jan 2011   USM Short Term